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KMID : 0360220150560040598
Journal of the Korean Ophthalmological Society
2015 Volume.56 No. 4 p.598 ~ p.601
A Case of Carcinoma Ex Pleomorphic Adenoma at 1st Operation
Jeon Soo-Ji

Kim Su-Ah
Paik Ji-Sun
Yang Suk-Woo
Abstract
Purpose: To report a case of carcinoma ex pleomorphic adenoma observed during the patient¡¯s first operation.

Case summary: A 63-year-old female presented with proptosis and ptosis that was aggravated 1 year prior. On preoperative CT image, a 32 x 20 x 21 mm-sized well demarcated mass (suspected as pleomorphic adenoma) was observed and was removed entirely by anterolateral orbitotomy. The excised mass surface was uneven but the capsule appeared intact on gross examination. Hard, yellow-colored and soft, dark-colored materials were found concurrently on cross section. The histological examination showed malignant cells as part of the soft material and was diagnosed as carcinoma ex pleomorphic adenoma.

Conclusions: We report a case of carcinoma ex pleomorphic adenoma of the lacrimal gland that presented with malignant change during the patient¡¯s first operation. Supposedly, during the process of mass growth, minimal rupture occurred causing malignant transformation. Clinically, although a mass is believed benign based on imaging, the possibility of malignant transformation of a tumor increasing rapidly or enlargement causing development of rapid proptosis should be considered.
KEYWORD
Carcinoma ex pleomorphic adenoma, Lacrimal gland tumor, Malignant mixed tumor, Pleomorphic adenoma
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